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As the American frontier bleeds into civilization, the legendary Van der Linde gang faces destruction from both the law outside and the venom within. Driven by the grand promises of Dutch (Jeffrey Dean Morgan), enforced by the conflicted muscle of Arthur Morgan (Jensen Ackles) and haunted by the fractured loyalty of a young John Marston (Wes Bentley). The gang's fate is pushed to the edge by the toxic ambition of Micah Bell (Ben Foster).